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Line bottom and sides of an 8-inch square baking pan with parchment paper, then lightly butter parchment.
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Bring cream, butter, vanilla, vanilla beans, pods, and fleur de sel to a boil in a small saucepan, then remove from heat and set aside.
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Boil sugar, corn syrup, and water in a 3- to 4-quart heavy saucepan, stirring until sugar is dissolved.
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Boil, without stirring, but gently swirling pan, until mixture is a light golden caramel.
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Remove pods and carefully stir cream mixture into the caramel (mixture will bubble up) and simmer, stirring frequently, until caramel registers 248 degrees F on candy thermometer.
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Pour into lined baking pan and cool 30 minutes.
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Sprinkle another pinch or two of fleur de sel over the top of the caramel (optional) for a nice salty crunch and let sit until completely cooled.
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Cut into 1-inch pieces (I buttered a pizza cutter), and then wrap each piece in a 4-inch square of wax paper, twisting 2 ends to close.