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Preheat oven to 350 degrees. Line two cupcake pans with liners and set aside.
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In a medium bowl, mix flour baking soda and salt and set aside.
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In another bowl mix beat butter, sugar and vanilla bean seeds until fluffy, about three minutes.
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Add eggs one at a time beating until smooth, scraping down the sides of the bowl between each egg.
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Mix in vanilla extract and buttermilk.
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Add one third of flour mixture, alternating with buttermilk mixture until combined, and ending with the flour mixture.
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Fill cupcake cups two thirds the way full and bake for 18-20 minutes or until a the cupcake springs back.
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Remove cupcakes and cool on rack.